Changes to the tax system will raise an extra 2bn Australian dollars ($1.5bn; £1.2bn) in this tax year, the government said.
A new law targets global companies with annual incomes of more than A$1bn.
Firms were told if they did not pay what was due they would be taxed at a penalty rate of 40%.
BBC reports that Australian Treasurer Scott Morrison said the government had given the Australian Taxation Office “the power, the resources and the penalties to get the job done”.
He said that Australian tax authorities were currently conducting 71 audits involving 59 major global corporations.
According to the government there were 30 global corporations that paid little or no tax on the profits from their Australian operations when the Multinational Anti-Avoidance Law was proposed in early 2015.
The Australian Tax Office was given a 1,000-person strong team of tax avoidance specialists to focus on large companies and wealthy individuals avoiding tax.
Posted by Juliet Ekwebelam